News - Customized Transgenic Mouse and Rat Models

LRP4 mouse model helps to understand rare skeletal disease June 1, 2017polygene
Sclerosteosis is a rare autosomal recessive bone disorder marked by excessive bone growth of the skull and tubular bones. Up to now, research showed: sclerosteosis was caused by loss-of-function mutations in the SOST gene, encoding sclerostin.
Recently, researchers within the european SYBIL consortium identified disease causing mutations in LRP4, a binding partner of sclerostin, ...
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Inspiring ECTS meeting and PolyGene seminar continued May 25, 2017polygene
Last tuesday ended the 44th European Calcified Tissue Society Congress (ECTS) in Salzburg, Austria and PolyGene looks back on vivid talks and fruitful networking.
Every year, ECTS creates a platform for researchers and clinicians working in the musculoskeletal field to strengthen collaborations and discuss the latest advances.
PolyGene brings great expertise in developing relevant ...
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Sclerosteosis is a rare autosomal recessive bone disorder marked by excessive bone growth of the skull and tubular bones. Up to now, research showed: sclerosteosis was caused by loss-of-function mutations in the SOST gene, encoding sclerostin.